Pharmacophore-Based Virtual Screening of Novel GSTP1-1 Inhibitors

Glutathione transferase enzymes play an important role in metabolism and detoxification of numerous xenobiotics, electrophilic drugs, environmental carcinogens, and products of oxidative stress in living organisms. Human GST P1-1 is the most prevalent isoform of the mammalian cytosolic GSTs and this...

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Bibliographic Details
Main Authors: Kayhan Bolelli, Tugba Ertan-Bolelli
Format: Article
Language:English
Published: Turkish Chemical Society 2018-11-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
Online Access:http://dergipark.gov.tr/jotcsa/issue/37193/466458