Altered Motoneuron Properties Contribute to Motor Deficits in a Rabbit Hypoxia-Ischemia Model of Cerebral Palsy

Altered Motoneuron Properties Contribute to Motor Deficits in a Rabbit Hypoxia-Ischemia Model of Cerebral Palsy

Cerebral palsy (CP) is caused by a variety of factors attributed to early brain damage, resulting in permanently impaired motor control, marked by weakness and muscle stiffness. To find out if altered physiology of spinal motoneurons (MNs) could contribute to movement deficits, we performed whole-ce...

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Bibliographic Details
Main Authors: Preston R. Steele, Clarissa Fantin Cavarsan, Lisa Dowaliby, Megan Westefeld, N. Katenka, Alexander Drobyshevsky, Monica A. Gorassini, Katharina A. Quinlan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebral palsy
hypoxia-ischemia
frequency-current
persistent inward current
rabbit
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00069/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00069/full

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