NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes

Abstract Background Neuroepithelial transforming gene 1 (NET1) is a RhoA subfamily guanine nucleotide exchange factor that governs a wide array of biological processes. However, its roles in meiotic oocyte remain unclear. We herein demonstrated that the NET1-HACE1-RAC1 pathway mediates meiotic defec...

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Bibliographic Details
Main Authors: Shiwei Wang, Xuan Wu, Mengmeng Zhang, Siyu Chang, Yajun Guo, Shuang Song, Shizhen Dai, Keliang Wu, Shenming Zeng
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-023-01177-4