Alterations in chromatin accessibility during osteoblast and adipocyte differentiation in human mesenchymal stem cells

Alterations in chromatin accessibility during osteoblast and adipocyte differentiation in human mesenchymal stem cells

Abstract Although differential expression of genes is apparent during the adipogenic/osteogenic differentiation of marrow mesenchymal stem cells (MSCs), it is not known whether this is associated with changes in chromosomal structure. In this study, we used ATAC-sequencing technology to observe vari...

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Bibliographic Details
Main Authors: Jianyun Liu, Lijun Gan, Baichen Ma, Shan He, Ping Wu, Huiming Li, Jianjun Xiong
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Medical Genomics
Subjects:
MSC
ATAC-seq
RNA-seq
Adipogenic
Osteogenic
Online Access:https://doi.org/10.1186/s12920-022-01168-1

Internet

https://doi.org/10.1186/s12920-022-01168-1

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