Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes

Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that acts as a critical mediator in the pathogenesis of atopic dermatitis (AD). Various therapeutic agents that prevent TSLP function can efficiently relieve the clinical symptoms of AD. However, the downregulation of TSLP ex...

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Bibliographic Details
Main Authors: Hyunjin Yeo, Young Han Lee, Sung Shin Ahn, Euitaek Jung, Yoongho Lim, Soon Young Shin
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
atopic dermatitis
chrysin
2,4-dinitrochlorobenzene
early growth response 1
thymic stromal lymphopoietin
Online Access:https://www.mdpi.com/1422-0067/22/9/4350

Internet

https://www.mdpi.com/1422-0067/22/9/4350

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