Design of a humanized anti vascular endothelial growth factor nanobody and evaluation of its in vitro function

Objective(s): Nanobodies, the single domain antigen binding fragments of heavy chain-only antibodies occurring naturally in camelid sera, are the smallest intact antigen binding entities. Their minimal size assists in reaching otherwise largely inaccessible regions of antigens. However, their cameli...

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Bibliographic Details
Main Authors: Fatemeh Kazemi-Lomedasht, serge muyldermans, Mahdi Habibi-Anbouhi, Mahdi Behdani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_10143_e44b4aa899dab4049b7201e92c53cd14.pdf