Anticancer Effects of 6-Gingerol through Downregulating Iron Transport and PD-L1 Expression in Non-Small Cell Lung Cancer Cells

Anticancer Effects of 6-Gingerol through Downregulating Iron Transport and PD-L1 Expression in Non-Small Cell Lung Cancer Cells

Iron homeostasis is considered a key factor in human metabolism, and abrogation in the system could create adverse effects, including cancer. Moreover, 6-gingerol is a widely used bioactive phenolic compound with anticancer activity, and studies on its exact mechanisms on non-small cell lung cancer...

Full description

Bibliographic Details
Main Authors: Dong Young Kang, Sanghyeon Park, Kyoung Seob Song, Se Won Bae, Jeong-Sang Lee, Kyoung-Jin Jang, Yeong-Min Park
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
NSCLC
6-gingerol
iron metabolism
oxidative stress
EGFR/JAK2/STAT5b signaling
PD-L1
Online Access:https://www.mdpi.com/2073-4409/12/22/2628

Internet

https://www.mdpi.com/2073-4409/12/22/2628

Similar Items