Brain-Derived Estrogen and Neurological Disorders

Brain-Derived Estrogen and Neurological Disorders

Astrocytes and neurons in the male and female brains produce the neurosteroid brain-derived 17β-estradiol (BDE<sub>2</sub>) from androgen precursors. In this review, we discuss evidence that suggest BDE<sub>2</sub> has a role in a number of neurological conditions, such as fo...

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Bibliographic Details
Main Authors: Darrell W. Brann, Yujiao Lu, Jing Wang, Gangadhara R. Sareddy, Uday P. Pratap, Quanguang Zhang, Rajeshwar R. Tekmal, Ratna K. Vadlamudi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biology
Subjects:
estradiol
neuroestrogen
neurosteroid
aromatase
cerebral ischemia
Alzheimer’s disease
Online Access:https://www.mdpi.com/2079-7737/11/12/1698

Internet

https://www.mdpi.com/2079-7737/11/12/1698

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