Specific genetic aberrations of parathyroid in Chinese patients with tertiary hyperparathyroidism using whole-exome sequencing

Specific genetic aberrations of parathyroid in Chinese patients with tertiary hyperparathyroidism using whole-exome sequencing

BackgroundTertiary hyperparathyroidism (THPT) is a peculiar subtype of hyperparathyroidism that usually develops from chronic kidney disease (CKD) and persists even after kidney transplantation. Unlike its precursor, secondary hyperparathyroidism (SHPT), THPT is characterized by uncontrolled high le...

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Bibliographic Details
Main Authors: Lei Li, Qixuan Sheng, Huajin Zeng, Wei Li, Qiang Wang, Guanjun Ma, Xinyun Xu, Ming Qiu, Wei Zhang, Chengxiang Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
tertiary hyperparathyroidism
whole-exome sequencing
somatic mutation
driver mutation
copy number variants
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1221060/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1221060/full

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