Exploratory Longitudinal Study of Ocular Structural and Visual Functional Changes in Subjects at High Genetic Risk of Developing Alzheimer’s Disease

Exploratory Longitudinal Study of Ocular Structural and Visual Functional Changes in Subjects at High Genetic Risk of Developing Alzheimer’s Disease

This study aimed to analyze the evolution of visual changes in cognitively healthy individuals at risk for Alzheimer’s disease (AD). Participants with a first-degree family history of AD (FH+) and carrying the Ε4+ allele for the ApoE gene (ApoE ε4+) underwent retinal thickness analysis using optical...

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Bibliographic Details
Main Authors: Inés López-Cuenca, Lidia Sánchez-Puebla, Elena Salobrar-García, María Álvarez-Gutierrez, Lorena Elvira-Hurtado, Ana Barabash, Federico Ramírez-Toraño, José A. Fernández-Albarral, José A. Matamoros, Alberto Nebreda, Alejandra García-Colomo, Ana I. Ramírez, Juan J. Salazar, Pedro Gil, Fernando Maestú, José M. Ramírez, Rosa de Hoz
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
Alzheimer’s disease
genetic risk
familiar history
ApoE ε4
optical coherence tomography
visual acuity
Online Access:https://www.mdpi.com/2227-9059/11/7/2024

Internet

https://www.mdpi.com/2227-9059/11/7/2024

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