In Silico Prediction and Prioritization of Novel Selective Antimicrobial Drug Targets in <i>Escherichia coli</i>

Novel antimicrobials interfering with pathogen-specific targets can minimize the risk of perturbations of the gut microbiota (dysbiosis) during therapy. We employed an in silico approach to identify essential proteins in <i>Escherichia coli</i> that are either absent or have low sequence...

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Bibliographic Details
Main Authors: Frida Svanberg Frisinger, Bimal Jana, Stefano Donadio, Luca Guardabassi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/6/632