Bilateral double site (calvarial and mandibular) critical-size bone defect model in rabbits for evaluation of a craniofacial tissue engineering constructs

Most existing preclinical models for evaluating the biosafety and bone-regeneration efficacy of innovative bone substitute materials (BSMs) or tissue engineering (TE) constructs only consisted of a single-site defect and the anatomical locations of defect varied drastically. While the compelling evide...

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Bibliographic Details
Main Authors: S. Kotagudda Ranganath, M. Schlund, Jérôme Delattre, J. Ferri, F. Chai
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422000655