A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78

Abstract Background Cells can die through a process called apoptosis in both pathological and healthy conditions. Cancer development and progression may result from abnormal apoptosis. The 78-kDa glucose-regulated protein (GRP78) is increased on the surface of cancer cells. Kringle 5, a cell apoptos...

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Bibliographic Details
Main Authors: Ibrahim Khater, Aaya Nassar
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Molecular and Cell Biology
Subjects:
Online Access:https://doi.org/10.1186/s12860-023-00484-3