Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series

Abstract Background Mechanically ventilated patients with COVID-19 have a mortality of 24–53%, in part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil extracellular traps (NETs) contribute to the viscosity of mucopurulent secretions and NETs are found in the s...

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Bibliographic Details
Main Authors: Andrew G. Weber, Alice S. Chau, Mikala Egeblad, Betsy J. Barnes, Tobias Janowitz
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Medicine
Subjects:
SARS-CoV-2
COVID-19
Coronavirus
Mucopurulent secretions
Dornase alfa
Neutrophil extracellular traps
Online Access:http://link.springer.com/article/10.1186/s10020-020-00215-w

Internet

http://link.springer.com/article/10.1186/s10020-020-00215-w

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