Venn Diagrams May Indicate Erroneous Statistical Reasoning in Transcriptomics

A common application of differential expression analysis is finding genes that are differentially expressed upon treatment in only one out of several groups of samples. One of the approaches is to test for significant difference in expression between treatment and control separately in the two group...

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Bibliographic Details
Main Authors: January Weiner, Benedikt Obermayer, Dieter Beule
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.818683/full