Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H2O2 enhances their ability to treat intervertebral disc degeneration

Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H2O2 enhances their ability to treat intervertebral disc degeneration

Abstract Background Nucleus pulposus mesenchymal stem cells (NPMSCs) transplantation is a promising treatment for intervertebral disc degeneration (IVDD). However, the transplanted NPMSCs exhibited weak cell proliferation, high cell apoptosis, and a low ability to resist the harsh microenvironment o...

Full description

Bibliographic Details
Main Authors: Yu-yao Zhang, Zhi-lei Hu, Yu-han Qi, Hai-yin Li, Xian Chang, Xiao-xin Gao, Chen-hao Liu, Yue-yang Li, Jin-hui Lou, Yu Zhai, Chang-qing Li
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
NPMSCs
H2O2
Pretreatment
Transplantation
IVDD
Online Access:https://doi.org/10.1186/s13287-022-03031-7

Internet

https://doi.org/10.1186/s13287-022-03031-7

Similar Items