Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

<p>Abstract</p> <p>Background</p> <p>Alefacept (anti-CD2) biological therapy selectively targets effector memory T cells (Tem) in psoriasis vulgaris, a model Type 1 autoimmune disease.</p> <p>Methods</p> <p>Circulating leukocytes were phenotyped...

Full description

Bibliographic Details
Main Authors: Novitskaya Inna, Khatcherian Artemis, Cardinale Irma, Sullivan-Whalen Mary, Gilleaudeau Patricia, Kikuchi Toyoko, Lee Edmund, Lin Shao-Lee, Chamian Francesca, Wittkowski Knut M, Krueger James G, Lowes Michelle A
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/27

Internet

http://www.translational-medicine.com/content/5/1/27

Similar Items