Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in MiceSummary

Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in MiceSummary

Background & Aims: The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here, we report that O-GlcNAcylation, an intracellular post-translational modification regulated by 2 enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a c...

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Bibliographic Details
Main Authors: Dakota R. Robarts, Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy, Norman Lee, Hartmut Jaeschke, Sumedha Gunewardena, Stephen A. Whelan, John A. Hanover, Natasha E. Zachara, Chad Slawson, Udayan Apte
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Cell Death
HNF4alpha
Proliferation
Partial Hepatectomy
Regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22000145

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X22000145

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