Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells

Propionic acid induces alterations in mitochondrial morphology and dynamics in SH-SY5Y cells

Abstract Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt mitochondrial biogenesis, metabolism, and turnover. However, the effect of PPA on mitochondrial dynamics, fission, and fusion...

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Bibliographic Details
Main Authors: Erin Buchanan, Caitlyn Mahony, Sophia Bam, Mohamed Jaffer, Sarah Macleod, Asandile Mangali, Mignon van der Watt, Sholto de Wet, Rensu Theart, Caron Jacobs, Ben Loos, Colleen O’Ryan
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40130-8

Internet

https://doi.org/10.1038/s41598-023-40130-8

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