HIGH LEUKEMIC STEM CELL FREQUENCY IN FLT3- MUTATED ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE: IMPLICATIONS FOR PROGNOSIS

HIGH LEUKEMIC STEM CELL FREQUENCY IN FLT3- MUTATED ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE: IMPLICATIONS FOR PROGNOSIS

Normal karyotype in Acute Myeloid Leukemia (NK-AML) occurs in 40-50% of patients. Leukemic Stem Cells (LSC) persistence is known to trigger relapse, but the prognostic impact of their identification is understudied. We correlated LSC frequency at diagnosis with mutational profile and clinical outcom...

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Bibliographic Details
Main Authors: CAB Garcia, LO Marani, M Medeiros, MIA Madeira, K Pagnano, E Nunes, ABF Glória, EM Rego, AG Carvalho, F Traina, LL Figueiredo-Pontes
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924009209

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http://www.sciencedirect.com/science/article/pii/S2531137924009209

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