Functional Biomarkers for Amyotrophic Lateral Sclerosis

The clinical diagnosis of amyotrophic lateral sclerosis (ALS) relies on determination of progressive dysfunction of both cortical as well as spinal and bulbar motor neurons. However, the variable mix of upper and lower motor neuron signs result in the clinical heterogeneity of patients with ALS, res...

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Bibliographic Details
Main Authors: William Huynh, Thanuja Dharmadasa, Steve Vucic, Matthew C. Kiernan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01141/full