Calpain-2 mediates SARS-CoV-2 entry via regulating ACE2 levels

Calpain-2 mediates SARS-CoV-2 entry via regulating ACE2 levels

ABSTRACTSince the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has been dedicated to identifying effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of calpain inhibitors show excellent antiviral activities against SARS-Co...

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Bibliographic Details
Main Authors: Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B. Kutluay, Matthew A. Ciorba, Siyuan Ding
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
SARS-CoV-2
viral entry
antivirals
Online Access:https://journals.asm.org/doi/10.1128/mbio.02287-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02287-23

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