Genotype-phenotype associations in neurofibromatosis type 1 (NF1): an increased risk of tumor complications in patients with <it>NF1</it> splice-site mutations?

Genotype-phenotype associations in neurofibromatosis type 1 (NF1): an increased risk of tumor complications in patients with <it>NF1</it> splice-site mutations?

<p>Abstract</p> <p>Neurofibromatosis type 1 (NF1) is a complex neurocutaneous disorder with an increased susceptibility to develop both benign and malignant tumors but with a wide spectrum of inter and intrafamilial clinical variability. The establishment of genotype-phenotype asso...

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Bibliographic Details
Main Authors: Alkindy Adila, Chuzhanova Nadia, Kini Usha, Cooper David N, Upadhyaya Meena
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Human Genomics
Subjects:
Neurofibromatosis type 1
Genotype-phenotype correlation
Malignant peripheral nerve sheath tumors
Brain glioma
Increased cancer susceptibility
Splice-site mutations
<it>NF1</it> gene
Gender effect
Online Access:http://www.humgenomics.com/content/6/1/12

Internet

http://www.humgenomics.com/content/6/1/12

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