Identification and functional comparison of novel alternatively spliced isoforms of human YAP

Identification and functional comparison of novel alternatively spliced isoforms of human YAP

As a key effector of the Hippo pathway, yes‐associated protein (YAP) is a major regulator of cell proliferation and apoptosis. In this study, 23 hYAP isoforms were identified in HEK293 cells, with 14 isoforms being reported for the first time. These isoforms were classified into hYAP‐a and hYAP‐b is...

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Bibliographic Details
Main Authors: Lianlian Liu, Junlei Zhang, Jiaqi Wang, Yanping Tian, Jiali Wang, Yixiao Xu, Yuda Cheng, Meng Yu, Jiangjun Wang, Yi Yang, Xueyue Wang, Ran Yang, Wei Wu, Chen Zhang, Yan Hu, Rui Jian, Lan Xiao, Yan Ruan
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:FEBS Open Bio
Subjects:
alternative splicing
cell chemosensitivity
transcriptional activation ability
YAP
Online Access:https://doi.org/10.1002/2211-5463.13618

Internet

https://doi.org/10.1002/2211-5463.13618

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