Micro-ecology restoration of colonic inflammation by in-Situ oral delivery of antibody-laden hydrogel microcapsules

Micro-ecology restoration of colonic inflammation by in-Situ oral delivery of antibody-laden hydrogel microcapsules

In-situ oral delivery of therapeutic antibodies, like monoclonal antibody, for chronic inflammation treatment is the most convenient approach compared with other administration routes. Moreover, the abundant links between the gut microbiota and colonic inflammation indicate that the synergistic or a...

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Bibliographic Details
Main Authors: Bo Li, Xin Li, Xiaodong Chu, Pengcheng Lou, Yin Yuan, Aoxiang Zhuge, Xueling Zhu, Yangfan Shen, Jinghua Pan, Liyuan Zhang, Lanjuan Li, Zhongwen Wu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-09-01
Series:Bioactive Materials
Subjects:
Antibody oral delivery
Hydrogel thin-shell microcapsules
Microfluidic
Gut microbiota
Colonic inflammation
Micro-ecology restoration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2100596X

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http://www.sciencedirect.com/science/article/pii/S2452199X2100596X

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