Antiviral Mechanism of Virucidal Sialic Acid Modified Cyclodextrin

We have reported that CD-6′SLN [6-sialyllactosamine (6′SLN)-modified β-cyclodextrin (CD)] can be a potential anti-influenza drug because it irreversibly deactivates virions. Indeed, in vivo, CD-6′SLN improved mice survival in an H1N1 infection model even when administered 24 h post-infection. Althou...

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Bibliographic Details
Main Authors: Yong Zhu, Andrey A. Sysoev, Paulo H. Jacob Silva, Marine Batista, Francesco Stellacci
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/2/582