Bronchial epithelial transcriptomics and experimental validation reveal asthma severity-related neutrophilc signatures and potential treatments

Abstract Airway epithelial transcriptome analysis of asthma patients with different severity was used to disentangle the immune infiltration mechanisms affecting asthma exacerbation, which may be advantageous to asthma treatment. Here we introduce various bioinformatics methods and develop two model...

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Bibliographic Details
Main Authors: Qian Yan, Xinxin Zhang, Yi Xie, Jing Yang, Chengxin Liu, Miaofen Zhang, Wenjiang Zheng, Xueying Lin, Hui-ting Huang, Xiaohong Liu, Yong Jiang, Shao-feng Zhan, Xiufang Huang
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05837-y