BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons

BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons

Brain-derived neurotrophic factor (BDNF) is widely reported to enhance synaptic vesicle (SV) exocytosis and neurotransmitter release. But it is still unclear whether BDNF enhances SV recycling at excitatory terminals only, or at both excitatory and inhibitory terminals. In the present study, in a di...

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Bibliographic Details
Main Authors: Yo eShinoda, Saheeb eAhmed, Binu eRamachandran, Vinita eBharat, David eBrockelt, Bekir eAltas, Camin eDean
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Brain-Derived Neurotrophic Factor
Exocytosis
neurotransmitter release
hippocampal neurons
excitatory / inhibitory
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00027/full

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