Biosynthesis, mode of action and functional significance of neurosteroids in the Purkinje cell

The brain has traditionally been considered to be a target site of peripheral steroid hormones. In addition to this classical concept, we now know that the brain has the capacity to synthesize steroids de novo from cholesterol, the so-called neurosteroids. In the middle 1990s, the Purkinje cell, an...

Full description

Bibliographic Details
Main Authors: Kazuyoshi eTsutsui, Kazuyoshi eUkena, Hirotaka eSakamoto, Shin-ichiro eOkuyama, Shogo eHaraguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00061/full