Qualitative Assay to Detect Dopamine Release by Ligand Action on Nicotinic Acetylcholine Receptors

Qualitative Assay to Detect Dopamine Release by Ligand Action on Nicotinic Acetylcholine Receptors

A pheochromocytoma of the rat adrenal medulla derived (a.k.a. PC12) cell-based assay for dopamine measurement by luminescence detection was customized for the qualitative evaluation of agonists and antagonists of nicotinic acetylcholine receptors (nAChRs). The assay mechanism begins with ligand bind...

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Bibliographic Details
Main Authors:	Leanna A. Marquart, Matthew W. Turner, Owen M. McDougal
Format:	Article
Language:	English
Published:	MDPI AG 2019-11-01
Series:	Toxins
Subjects:	pc12 cells alpha-conotoxin nicotinic acetylcholine receptor dopamine luminescence assay
Online Access:	https://www.mdpi.com/2072-6651/11/12/682

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