Discovery of new indolosesquiterpenoids bearing a N-O linkage by overexpression of LuxR regulator in a marine bacterium Streptomyces sp.

Discovery of new indolosesquiterpenoids bearing a N-O linkage by overexpression of LuxR regulator in a marine bacterium Streptomyces sp.

The xiamycins are bioactive indolosesquiterpenoids that have been isolated from actinobacterial strains belonging to the Streptomyces genus. The overexpression of orf2011, which encodes the LuxR family regulator in a marine Streptomyces strain (HK18) isolated from a hypersaline saltern, significantl...

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Bibliographic Details
Main Authors: Jiyoon Park, Hang Su Cho, Dong Hyun Moon, Donghoon Lee, Youngjoo Kal, Sangwon Cha, Sang Kook Lee, Yeo Joon Yoon, Dong-Chan Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Marine Science
Subjects:
indolosesquiterpenoid
bacteria
overexpression
N-O bond
structure elucidation
Online Access:https://www.frontiersin.org/articles/10.3389/fmars.2023.1140516/full

Internet

https://www.frontiersin.org/articles/10.3389/fmars.2023.1140516/full

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