Prion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and voles.

Prion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and voles.

The bank vole is a rodent susceptible to different prion strains from humans and various animal species. We analyzed the transmission features of different prions in a panel of seven rodent species which showed various degrees of phylogenetic affinity and specific prion protein (PrP) sequence diverg...

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Bibliographic Details
Main Authors: Umberto Agrimi, Romolo Nonno, Giacomo Dell'Omo, Michele Angelo Di Bari, Michela Conte, Barbara Chiappini, Elena Esposito, Giovanni Di Guardo, Otto Windl, Gabriele Vaccari, Hans-Peter Lipp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2453331?pdf=render

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http://europepmc.org/articles/PMC2453331?pdf=render

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