Isoflurane-Induced Burst Suppression Is a Thalamus-Modulated, Focal-Onset Rhythm With Persistent Local Asynchrony and Variable Propagation Patterns in Rats

Isoflurane-Induced Burst Suppression Is a Thalamus-Modulated, Focal-Onset Rhythm With Persistent Local Asynchrony and Variable Propagation Patterns in Rats

Background: Inhalational anesthetic-induced burst suppression (BS) is classically considered a bilaterally synchronous rhythm. However, local asynchrony has been predicted in theoretical studies and reported in patients with pre-existing focal pathology.Method: We used high-speed widefield calcium i...

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Bibliographic Details
Main Authors: Qianwen Ming, Jyun-You Liou, Fan Yang, Jing Li, Chaojia Chu, Qingchen Zhou, Dan Wu, Shujia Xu, Peijuan Luo, Jianmin Liang, Dan Li, Kane O. Pryor, Weihong Lin, Theodore H. Schwartz, Hongtao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Systems Neuroscience
Subjects:
general anesthesia
burst suppression
widefield calcium imaging
thalamocortical interactions
traveling wave
slow oscillations
Online Access:https://www.frontiersin.org/articles/10.3389/fnsys.2020.599781/full

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https://www.frontiersin.org/articles/10.3389/fnsys.2020.599781/full

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