Genetically Engineered Cellular Nanovesicle as Targeted DNase I Delivery System for the Clearance of Neutrophil Extracellular Traps in Acute Lung Injury

Genetically Engineered Cellular Nanovesicle as Targeted DNase I Delivery System for the Clearance of Neutrophil Extracellular Traps in Acute Lung Injury

Abstract Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are prevalent critical illnesses with a high mortality rate among patients in intensive care units. Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of ALI/ARDS and represent a promising therapeutic t...

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Bibliographic Details
Main Authors: Yang Du, Yining Chen, Fangyuan Li, Zhengwei Mao, Yuan Ding, Weilin Wang
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
acute lung injury
biomimetic nanovesicles
bioorthogonal chemistry
genetic engineering
neutrophil extracellular traps
protein delivery
Online Access:https://doi.org/10.1002/advs.202303053

Internet

https://doi.org/10.1002/advs.202303053

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