HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape

HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape

HIV and Schistosoma infections have been individually associated with pulmonary vascular disease. Co-infection with these pathogens is very common in tropical areas, with an estimate of six million people co-infected worldwide. However, the effects of HIV and Schistosoma co-exposure on the pulmonary...

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Bibliographic Details
Main Authors: Sandra Medrano-Garcia, Daniel Morales-Cano, Bianca Barreira, Alba Vera-Zambrano, Rahul Kumar, Djuro Kosanovic, Ralph Theo Schermuly, Brian B. Graham, Francisco Perez-Vizcaino, Alistair Mathie, Rajkumar Savai, Soni Pullamseti, Ghazwan Butrous, Edgar Fernández-Malavé, Angel Cogolludo
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
HIV
schistosomiasis
pulmonary arterial hypertension
inflammation
pulmonary endothelium
pulmonary vascular remodeling
Online Access:https://www.mdpi.com/2073-4409/11/15/2414

Internet

https://www.mdpi.com/2073-4409/11/15/2414

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