Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis
Abstract Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. One of the reported contributors to ALS pathology is mitochondrial d...
Main Authors: | Amit U Joshi, Nay L Saw, Hannes Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria Mochly‐Rosen |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2018-03-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.201708166 |
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