Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines

Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines

FA esters of hydroxy FAs (FAHFAs) are lipokines with extensive structural and regional isomeric diversity that impact multiple physiological functions, including insulin sensitivity and glucose homeostasis. Because of their low molar abundance, FAHFAs are typically quantified using highly sensitive...

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Bibliographic Details
Main Authors: Alisa B. Nelson, Lisa S. Chow, Curtis C. Hughey, Peter A. Crawford, Patrycja Puchalska
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Lipid Research
Subjects:
insulin resistance
lipidomics
lipids
obesity
adipose tissue
LC-MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522000347

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http://www.sciencedirect.com/science/article/pii/S0022227522000347

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