A qualitative transcriptional signature to reclassify histological grade of ER-positive breast cancer patients

A qualitative transcriptional signature to reclassify histological grade of ER-positive breast cancer patients

Abstract Background Histological grade (HG) is commonly adopted as a prognostic factor for ER-positive breast cancer patients. However, HG evaluation methods, such as the pathological Nottingham grading system, are highly subjective with only 50–85% inter-observer agreements. Specifically, the subje...

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Bibliographic Details
Main Authors: Jing Li, Wenbin Jiang, Qirui Liang, Guanghao Liu, Yupeng Dai, Hailong Zheng, Jing Yang, Hao Cai, Guo Zheng
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Genomics
Subjects:
Histological grade
ER-positive breast cancer
Gene expression
Survival analysis
Online Access:http://link.springer.com/article/10.1186/s12864-020-6659-0

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http://link.springer.com/article/10.1186/s12864-020-6659-0

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