Synaptic vesicle docking: sphingosine regulates syntaxin1 interaction with Munc18.
Consensus exists that lipids must play key functions in synaptic activity but precise mechanistic information is limited. Acid sphingomyelinase knockout mice (ASMko) are a suitable model to address the role of sphingolipids in synaptic regulation as they recapitulate a mental retardation syndrome, N...
Main Authors: | , , , , , , , , |
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Format: | Article |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2009-01-01
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Serija: | PLoS ONE |
Online dostop: | http://europepmc.org/articles/PMC2668795?pdf=render |