Therapeutic potential of elafin in airway inflammatory disease

Elafin, which is derived from trappin-2 or pre-elafin by proteolysis, is an endogenous serine protease inhibitor with a low molecular weight. Its inhibitory activity is dependent on anchoring to the extracellular matrix by forming covalent bonds with its distinctive N-terminal domain via tissue tran...

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Bibliographic Details
Main Authors: Mingxin He, Yalou Yang, Yanyan Li, Xiangdong Zhou, Li Xu, Ziwei Zhang, Hua Zhang, Qi Li
Format: Article
Language:English
Published: SAGE Publishing 2024-02-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X241237437