Patient‐derived pancreatic tumour organoid implantation establishes novel pre‐cachexia mouse models

Patient‐derived pancreatic tumour organoid implantation establishes novel pre‐cachexia mouse models

Abstract Background The poor survival of pancreatic cancer patients is largely attributable to cachexia, a syndrome of severe weight and muscle loss. To investigate the aetiology of cancer cachexia, preclinical models that closely recapitulate the human disease process are essential. Patient derived...

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Bibliographic Details
Main Authors: Merel R. Aberle, Rianne D.W. Vaes, Wouter R.P.H. van deWorp, Ludwig J. Dubois, Natasja G. Lieuwes, Rianne Biemans, Ramon C.J. Langen, Frederik‐Jan vanSchooten, Ronald M. vanDam, Steven W.M. Olde Damink, Sander S. Rensen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:JCSM Rapid Communications
Subjects:
Sarcopenia
Ubiquitin proteasome
Xenograft
Inflammation
Online Access:https://doi.org/10.1002/rco2.71

Internet

https://doi.org/10.1002/rco2.71

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