Immunotherapy of cancer tumors with inhibition of PD-1 membrane protein and its ligands interaction

The identification of the PD-1 receptor by Tasuku Honjo and CTLA-4 by James Ellison marked the beginning of the study of new regulatory pathways activating the immune response. The term “immune checkpoints” was introduced to denote the system of inhibitory mechanisms that include these proteins. The...

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Bibliographic Details
Main Authors: A. V. Chetveryakov, V. L. Tsepelev
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2021-10-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/2982