Propionate ameliorates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress

Propionate is a short chain fatty acid and abundant as butyrate in the gut and blood. However, propionate has been studied less extensively than butyrate in the treatment of colitis. The present study was to investigate the effects of sodium propionate on intestinal barrier function, inflammation an...

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Bibliographic Details
Main Authors: Lingchang Tong, Yue Wang, Zhi-bin Wang, Wei-ye Liu, Sheng Sun, Li-chao Zhang, Ding-feng Su, LING LI
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00253/full