Ataxia-telangiectasia Mutated Kinase (ATM) as a Central Regulator of Radiation-induced DNA Damage Response
Ataxia-telangiectasia mutated kinase (ATM) is a DNA damage-inducible protein kinase, which phosphorylates plethora of substrates participating in DNA damage response. ATM significance for the cell faith is undeniable, since it regulates DNA repair, cell-cycle progress, and apoptosis. Here we describ...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Karolinum Press
2010-01-01
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Series: | Acta Medica |
Subjects: | |
Online Access: | https://actamedica.lfhk.cuni.cz/53/1/0013/ |