C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection

C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection

The signalling mechanisms of costimulation in the development of memory T cells remain to be clarified. Here, we show that the transcription factor c-Myc in CD8+ T cells is controlled by costimulatory molecules, which modulates the development of memory CD8+ T cells. C-Myc expression was dramaticall...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, Jianxun Song
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: The Royal Society 2016-01-01
Sraith:Open Biology
Ábhair:
c-myc
costimulation
cd8+ t cells
memory
viral infection
Rochtain ar líne:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150208

Ar líne

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150208

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