Integrated Analysis of Cytokine Profiles in Malaria Patients Discloses Selective Upregulation of TGF-β1, β3, and IL-9 in Mild Clinical Presentation

Integrated Analysis of Cytokine Profiles in Malaria Patients Discloses Selective Upregulation of TGF-β1, β3, and IL-9 in Mild Clinical Presentation

The proper control of Plasmodium infection requires a finely balanced immune response. Here, we evaluated the implication of TGF-β1 and TGF-β3 in this process using novel monoclonal antibodies to measure their plasma concentrations in comparison with other cytokines and the expression of FOXP3 mRNA....

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Bibliographic Details
Main Authors: Ella Larissa Ndoricyimpaye, Jacques Van Snick, Jean de Dieu Niyoyita, Philbert Kanimba, Jean Bosco Mbonimpa, Robert Rutayisire, Réverien Rutayisire, Vedaste Ndahindwa, Paméla Cheou, Jean Paul Coutelier, Nadine Rujeni
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
malaria pattern
pro-inflammatory cytokines
parasite
regulatory cytokines
Tregs
Online Access:https://www.mdpi.com/1422-0067/23/20/12665

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https://www.mdpi.com/1422-0067/23/20/12665

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