Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings

Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings

A wide range of derivatives with new pyrido[2,1-a]pyrrolo[3,4-c]isoquinoline skeleton was synthesized by free-radical intramolecular cyclization of o-bromophenyl-substituted pyrrolylpyridinium salts using the (TMS)3SiH/AIBN system. The cyclization provides generally good yields of pyrido[2,1-a]pyrro...

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Bibliographic Details
Main Authors: Ivan P. Mosiagin, Olesya A. Tomashenko, Dar’ya V. Spiridonova, Mikhail S. Novikov, Sergey P. Tunik, Alexander F. Khlebnikov
Format: Article
Language:English
Published: Beilstein-Institut 2021-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
arylation
pyridine
pyrrole
radical cyclization
tris(trimethylsilyl)silane
Online Access:https://doi.org/10.3762/bjoc.17.105

Internet

https://doi.org/10.3762/bjoc.17.105

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