The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics

The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics

BackgroundThe MTNR1B gene encodes a receptor for melatonin, a hormone regulating biorhythms. Disruptions in biorhythms contribute to the development of type 2 diabetes mellitus (T2DM). Genetic studies suggest that variability in the MTNR1B gene affects T2DM development. Our aim was to compare the di...

Full description

Bibliographic Details
Main Authors: Daniela Vejrazkova, Marketa Vankova, Josef Vcelak, Hana Krejci, Katerina Anderlova, Andrea Tura, Giovanni Pacini, Alena Sumova, Martin Sladek, Bela Bendlova
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
type 2 daibetes mellitus
insulin sensitivity
beta cell function
MTNR1B gene
rs10830963
OGTT trajectories
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.868364/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.868364/full

Similar Items