<i>N</i>-acetyltaurine and Acetylcarnitine Production for the Mitochondrial Acetyl-CoA Regulation in Skeletal Muscles during Endurance Exercises

<i>N</i>-acetyltaurine and Acetylcarnitine Production for the Mitochondrial Acetyl-CoA Regulation in Skeletal Muscles during Endurance Exercises

During endurance exercises, a large amount of mitochondrial acetyl-CoA is produced in skeletal muscles from lipids, and the excess acetyl-CoA suppresses the metabolic flux from glycolysis to the TCA cycle. This study evaluated the hypothesis that taurine and carnitine act as a buffer of the acetyl m...

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Bibliographic Details
Main Authors: Teruo Miyazaki, Yuho Nakamura-Shinya, Kei Ebina, Shoichi Komine, Song-Gyu Ra, Keisuke Ishikura, Hajime Ohmori, Akira Honda
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
taurine
NAT
carnitine
ACT
acetyl-CoA
mitochondria
Online Access:https://www.mdpi.com/2218-1989/11/8/522

Internet

https://www.mdpi.com/2218-1989/11/8/522

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