[<sup>99m</sup>Tc]Tc-iFAP Radioligand for SPECT/CT Imaging of the Tumor Microenvironment: Kinetics, Radiation Dosimetry, and Imaging in Patients

[<sup>99m</sup>Tc]Tc-iFAP Radioligand for SPECT/CT Imaging of the Tumor Microenvironment: Kinetics, Radiation Dosimetry, and Imaging in Patients

Tumor microenvironment fibroblasts overexpress the fibroblast activation protein (FAP). We recently reported the preclinical evaluation of [<sup>99m</sup>Tc]Tc-iFAP as a new SPECT radioligand capable of detecting FAP. This research aimed to evaluate the kinetic and dosimetric profile of...

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Bibliographic Details
Main Authors: Luis Coria-Domínguez, Paola Vallejo-Armenta, Myrna Luna-Gutiérrez, Blanca Ocampo-García, Brenda Gibbens-Bandala, Francisco García-Pérez, Gerardo Ramírez-Nava, Clara Santos-Cuevas, Guillermina Ferro-Flores
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
fibroblast activation protein
FAP imaging
technetium-99m
[<sup>99m</sup>Tc]Tc-FAP inhibitor ligand
Online Access:https://www.mdpi.com/1424-8247/15/5/590

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https://www.mdpi.com/1424-8247/15/5/590

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